### Description

This column shows gene expression differences between adult male and female tissues as described in Rinn et al., "The major molecular differences between mammalian sexes are involved in drug metabolism and renal function", Developmental Cell 6(6), 791-800 (2004).

### Methods

Five adult mouse tissues liver, kidney, hypothalamus, ovary and testis, were studied. For each somatic tissue, triple selected poly-A mRNA was prepared from 6 independent pools (biological replicates), 3 male and 3 female. Likewise, 3 pools were prepared from the ovary and 3 pools from the testis. Each pool of RNA was derived from 10 individuals. Furthermore, for each biological replicate two cDNAs (technical replicates) were prepared and independently hybridized to Affymetrix MOE430A chips. The biological replicates are labeled with the numbers 1,2,3. The technical replicates are labeled A,B.

## Credits

Thanks to John Rinn for providing these data.